Endocrine Abstracts

Background: Children with Prader–Willi syndrome (PWS) have a predictable pattern of weight gain, with obesity beginning in early childhood and worsening as they get older. They have low tone and as a result their energy requirements are lower (typically 60% estimated average requirement for energy (EAR)) than age matched controls. We present three case studies of children with PWS who have been following a modified macronutrient diet, with significant positive changes to ...